In vitro fertilization (IVF) is an assisted reproductive technique for couples having difficulty conceiving, where fertilization occurs outside the body. The procedure involves five main stages that take approximately 4-6 weeks.

Stage 1: Ovulation Induction

The doctor stimulates the ovaries with hormones such as FSH, LH, and hCG for 1-2 weeks to produce multiple mature eggs. Monitoring is done via ultrasound and blood tests to ensure timely ovulation.

Stage 2: Egg Retrieval

The eggs are retrieved using a small needle guided by transvaginal ultrasound (follicular aspiration), usually 36 hours after the ovulation trigger injection. This procedure takes 20-30 minutes under light sedation, and the mature eggs are stored in an incubator.

Stage 3: Sperm Retrieval and Fertilization

Sperm is collected from the man via masturbation or a minor surgical procedure, if necessary. In the lab, the sperm is fertilized with the eggs using conventional techniques or ICSI (direct sperm-to-egg injection), resulting in embryos.

Stage 4: Embryo Culture

The embryos are cultured in an incubator for 3-5 days until they reach the blastocyst stage. The doctor checks their quality and performs genetic testing, if necessary, before selecting the best embryos.

Stage 5: Embryo Transfer

One or two embryos are transferred to the uterus via a thin catheter without anesthesia, approximately 3-5 days after egg retrieval. Pregnancy is confirmed two weeks later via a blood test; any remaining embryos can be frozen.

Estimated IVF Costs
Procedure Component Estimated Cost (IDR) Description
Consultation & Initial Screening Rp2,000,000 – Rp5,000,000 Husband & Wife
Stimulation & Hormonal Medication Rp25,000,000 – Rp45,000,000 Depending on the dose
Oocyte Pick-Up (OPU) Rp15,000,000 – Rp25,000,000 Egg Retrieval
Laboratory (ICSI/IMSI) Rp10,000,000 – Rp20,000,000 Fertilization in the Laboratory
Embryo Transfer (ET) Rp8,000,000 – Rp12,000,000 Embryo Implantation

“The success of an IVF program is determined not only by the technology, but also by the couple’s nutritional and mental preparation three months before starting the cycle.”
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