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Assisted hatching is a technique used in in vitro fertilization (IVF) to help embryos hatch more easily from their protective outer layer, called the zona pellucida. The goal of this procedure is to allow the embryo to implant more smoothly into the uterine wall. Assisted hatching is recommended for patients with a history of failed embryo implantation, age over 38, high embryo damage rate, thick zona pellucida, or if the embryo is from a previous freezing process.
Assisted hatching techniques use various methods, such as laser, mechanical, or chemical, to create a small hole or thin the zona pellucida. With easier access, the embryo has a better chance of hatching and implanting into the uterine wall. The assisted hatching procedure is not applied to every patient, but only in certain cases that are tailored to the individual patient’s medical condition.